MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20621047.
- Also identified by DOI 10.1016/j.stem.2010.06.011 and PMC identifier 4121883.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Understanding the molecular foundations of embryonic stem cell (ESC) self-renewal and pluripotency will facilitate therapeutic exploitation of these remarkable cells. Here we discuss the emerging roles of microRNAs in the establishment and maintenance of ESC identity and summarize our current understanding of the mechanisms controlling microRNA expression and function in ESCs.
Medical subject headings
- Embryonic Stem Cells
- MicroRNAs
- Signal Transduction