Population dynamics of natural antibodies in normal and autoimmune individuals.
Where this comes from
- Record sourced from PubMed, PMID 2062870.
- Also identified by PMC identifier 51989.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We have measured the quantities of naturally occurring autoantibodies in the serum of normal, unmanipulated individuals. These changes over time following broad-band complex dynamical patterns that are similar in mouse and man. The patterns more likely reflect the network architecture of the natural antibody repertoire, regulating the activation and decay of individual clones. The temporal changes of both disease-specific and nonspecific autoantibodies are consistently modified in autoimmune individuals.
Medical subject headings
- Antibodies
- Autoimmune Diseases
- Thyroiditis, Autoimmune