Evaluation of nonenhancing tumor fraction assessed by dynamic contrast-enhanced MRI subtraction as a predictor of decrease in tumor volume in response to chemoradiotherapy in advanced cervical cancer.

Mannelli, Lorenzo; Patterson, Andrew J; Zahra, Mark; Priest, Andrew N; Graves, Martin J; Lomas, David J; Tan, Li Tee; Crawford, Robin et al. · AJR Am J Roentgenol · 2010

case_series · Level IV

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Abstract

In this study, we evaluated the feasibility of using dynamic contrast-enhanced MRI (DCE-MRI) subtracted images as a predictor of a decrease in tumor volume in response to chemoradiotherapy in 13 patients with cervical cancer. This study shows that pretreatment tumor nonenhancing fraction assessed with arterial image subtraction inversely predicts the chemoradiation response in cervical cancer.

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