Combined therapy for thyroid squamous cell carcinoma.

De Vos, Filip Yves F L; Sewnaik, Aniel; de Wilt, J Hans W; Smid, Ernst J; den Bakker, Michael A; van Meerten, Esther · Head Neck · 2012

case_report · Level V

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Abstract

BACKGROUND.: Squamous carcinoma of the thyroid is a rare aggressive disease, resulting in poor prognosis. METHODS AND RESULTS.: We combined cisplatin with paclitaxel on a weekly basis as induction therapy, achieving a high cumulative dose, in a patient with squamous cell tumor of the thyroid with arterial encasement. After surgery, pathologic examination confirmed a complete resection of the primary tumor with clear margins, revealing a successful induction treatment with chemotherapy. CONCLUSIONS.: Our patient now has a recurrence-free survival of >20 months, longer than the mean survival described in the literature.

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