Profuse oral secretions after propafenone administration in neonates.

Piersigilli, Fiammetta; Auriti, Cinzia; Silvetti, Massimo Stefano; Marrocco, Gabriella; Drago, Fabrizio; Seganti, Giulio · J Pediatr · 2010

case_report · Level V

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Abstract

Propafenone, an antiarrhythmic drug that is effective for treating supraventricular tachycardias, can induce well-known proarrhythmic and systemic adverse effects. We describe a previously unreported adverse effect in 3 newborns: oral propafenone-induced profuse oral secretions and respiratory distress of sufficient severity to necessitate discontinuation of propafenone.

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