Therapeutic drug monitoring of mycophenolic acid: a potential treatment for lupus nephritis.
expert_opinion · Level V
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- Record sourced from PubMed, PMID 20671734.
- Also identified by DOI 10.1038/ki.2010.181.
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Abstract
Mycophenolate mofetil, an immunosuppressant approved for the prevention of transplant rejection, has been used in patients with lupus nephritis. Lertdumrongluk et al. suggest that mycophenolic acid exposure may predict therapeutic responses in severe lupus nephritis, and their initial results confirm that hypothesis. However, it seems that enteric-coated mycophenolate sodium should not be administered to patients provided with therapeutic drug monitoring.
Medical subject headings
- Drug Monitoring
- Lupus Nephritis
- Mycophenolic Acid