A clock ticks in pancreatic beta cells.
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- Record sourced from PubMed, PMID 20674854.
- Also identified by DOI 10.1016/j.cmet.2010.07.006 and PMC identifier 3739698.
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Abstract
Circadian rhythm is a pervasive feature of life, programmed by the conserved core clock machinery. A recent study in Nature (Marcheva et al., 2010) reveals that core clock components regulate beta cell function and integrate insulin secretion into rhythmic metabolic regulation, providing new insight into the pathogenesis of diabetes.