C-reactive protein is a bystander of cardiovascular disease.

Anand, Sonia S; Yusuf, Salim · Eur Heart J · 2010

review · Level V

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Abstract

A large number of studies have evaluated the association of hs-C-reactive protein with atherosclerosis and coronary heart disease (CHD) in mechanistic, genetic, population-based studies, as well as clinical trials. This paper reviews the collective evidence to determine if hs-C-reactive protein is part of the causal pathway of atherosclerosis and CHD or whether it is a bystander.

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