A preliminary study of the ocular hypotensive effects of bromocriptine in diabetic patients with autonomic neuropathy.
case_series · Level IV
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- Record sourced from PubMed, PMID 2068026.
- Also identified by PMC identifier 2398792.
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Abstract
The effect of bromocriptine on intraocular pressure has been investigated in a group of 8 diabetic patients with autonomic neuropathy, to test the hypothesis that bromocriptine exerts its ocular hypotensive action through presynaptic dopamine receptors. Bromocriptine eye drops (0.025%) produced a significant fall in intraocular pressure in a control group of 8 matched normal volunteers, but this effect was not seen in the eyes of the diabetic patients. These results are consistent with a presynaptic site of action of bromocriptine.
Medical subject headings
- Autonomic Nervous System Diseases
- Bromocriptine
- Diabetic Neuropathies
- Intraocular Pressure