Programmable periodicity of quantum dot arrays with DNA origami nanotubes.

Bui, Hieu; Onodera, Craig; Kidwell, Carson; Tan, YerPeng; Graugnard, Elton; Kuang, Wan; Lee, Jeunghoon; Knowlton, William B et al. · Nano Lett · 2010

basic_science · Level V

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Abstract

To fabricate quantum dot arrays with programmable periodicity, functionalized DNA origami nanotubes were developed. Selected DNA staple strands were biotin-labeled to form periodic binding sites for streptavidin-conjugated quantum dots. Successful formation of arrays with periods of 43 and 71 nm demonstrates precise, programmable, large-scale nanoparticle patterning; however, limitations in array periodicity were also observed. Statistical analysis of AFM images revealed evidence for steric hindrance or site bridging that limited the minimum array periodicity.

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