Dying alone: a tale of rho.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20682437.
- Also identified by DOI 10.1016/j.stem.2010.07.002.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In this issue of Cell Stem Cell, Chen et al. (2010) and Ohgushi et al. (2010) report that Rho-mediated actomyosin contractility underlies the proclivity of human embryonic stem cells to undergo apoptosis upon dissociation or during low-density propagation, a property that challenges their in vitro isolation and manipulation.