Keeping the epidermal stem cell niche in shape.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20682441.
- Also identified by DOI 10.1016/j.stem.2010.07.008.
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Abstract
Recently in Nature Cell Biology,Connelly et al. (2010) identified biomechanical sensing mechanisms that link the physical shape of the stem cell microenvironment to epithelial stem cell fate decisions. Ultimately, the integration of extrinsic and intrinsic signals controls stem cell self-renewal or differentiation.