Differential DNA damage response in stem and progenitor cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20682442.
- Also identified by DOI 10.1016/j.stem.2010.07.006.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The long lifespan of tissue-specific stem cells suggests that they may respond differently to DNA damage than downstream cells. In this issue of Cell Stem Cell, two groups address this hypothesis by examining DNA damage responses in hematopoietic stem and progenitor cells (Milyavsky et al., 2010; Mohrin et al., 2010).