Graft-induced dyskinesias in Parkinson's disease: what is it all about?

Barker, Roger A; Kuan, Wei-Li · Cell Stem Cell · 2010

review · Level V

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Abstract

The treatment of Parkinson's disease with grafts of fetal ventral mesencephalic tissue has shown some success, but can result in graft-induced dyskinesias (GIDs). Recently in Science Translational Medicine, Politis et al. (2010) demonstrate that GIDs may originate from serotoninergic neurons that are cografted in these transplants.

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