Noncoding RNAs: the missing "linc" in p53-mediated repression.
basic_science · Level V
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- Record sourced from PubMed, PMID 20691894.
- Also identified by DOI 10.1016/j.cell.2010.07.029.
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Abstract
The tumor suppressor protein p53 coordinates the cellular response to stress through regulation of gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a new player in p53-mediated repression of genes involved in apoptosis.