Mitochondrial matrix reloaded with RNA.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20691896.
- Also identified by DOI 10.1016/j.cell.2010.07.024.
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Abstract
Although mitochondrial biogenesis requires the import of specific RNAs, the pathways and cellular machineries involved are only poorly understood. Wang et al. (2010) now find that polynucleotide phosphorylase in the intermembrane space of mammalian mitochondria facilitates import of several RNAs into the mitochondrial matrix.