A MAP for bundling microtubules.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20691897.
- Also identified by DOI 10.1016/j.cell.2010.07.023.
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Abstract
Microtubules assemble into arrays of bundled filaments that are critical for multiple steps in cell division, including anaphase and cytokinesis. Recent structural and functional studies, including two papers in this issue of Cell (Bieling et al., 2010; Subramanian et al., 2010), demonstrate how the MAP65 protein PRC1 crosslinks microtubules and cooperates with kinesin motors to control the dynamics and size of bundled regions.
Medical subject headings
- Microtubule-Associated Proteins
- Microtubules
- Plants