RefProtDom: a protein database with improved domain boundaries and homology relationships.

Gonzalez, Mileidy W; Pearson, William R · Bioinformatics · 2010

basic_science · Level V

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Abstract

UNLABELLED: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications. AVAILABILITY: RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a.

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