Tuning hydrogel properties and function using substituent effects.
basic_science · Level V
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- Record sourced from PubMed, PMID 20694176.
- Also identified by PMC identifier 2915463.
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Abstract
The physical properties and function of hydrogels are shown to depend on the substituents present in three novel 1,3,5-tri-azaadamantane (TAA) cross-linkers. Gel stiffness and degradation rate at varied pHs could be predictably tuned with the cross-linker substituents used to form the gel. Subsequently, protein release from the hydrogel were controlled with chemical structure of the cross-linker.