In vitro and in vivo studies of single-walled carbon nanohorns with encapsulated metallofullerenes and exohedrally functionalized quantum dots.
basic_science · Level V
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- Record sourced from PubMed, PMID 20698597.
- Also identified by DOI 10.1021/nl1008635 and PMC identifier 2935139.
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Abstract
Single-walled carbon nanohorns (SWNHs) are new carbonaceous materials. In this paper, we report the first successful preparation of SWNHs encapsulating trimetallic nitride template endohedral metallofullerenes (TNT-EMFs). The resultant materials were functionalized by a high-speed vibration milling method and conjugated with CdSe/ZnS quantum dots (QDs). The successful encapsulation of TNT-EMFs and external functionalization with QDs provide a dual diagnostic platform for in vitro and in vivo biomedical applications of these new carbonaceous materials.
Medical subject headings
- Fullerenes
- Metals
- Nanotubes, Carbon
- Quantum Dots