Induced domain formation in endocytic invagination, lipid sorting, and scission.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20723749.
- Also identified by DOI 10.1016/j.cell.2010.08.007.
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Abstract
Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.
Medical subject headings
- Endocytosis
- Lipid Metabolism