Multicity outbreak of linezolid-resistant Staphylococcus epidermidis associated with clonal spread of a cfr-containing strain.

Bonilla, Hector; Huband, Michael D; Seidel, Joan; Schmidt, Helen; Lescoe, Marykay; McCurdy, Sandra P; Lemmon, M Megan; Brennan, Lori A et al. · Clin Infect Dis · 2010

case_series · Level IV

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Abstract

We report a multicity outbreak of cfr-containing linezolid-resistant Staphylococcus epidermidis in Ohio. Thirty-nine isolates were obtained from 2 hospitals. Two clones with different mechanisms of linezolid resistance were circulating in hospital A. One of these contained the cfr gene, and the other a ribosomal mutation. The clone containing cfr was identical in both hospitals.

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