Growth factors: beyond bone morphogenetic proteins.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20736791.
- Also identified by DOI 10.1097/BOT.0b013e3181ec4833.
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Abstract
The current landscape of growth factors in orthopaedic trauma is dominated by the BMPs, as they are the most extensively studied growth factors in clinical applications pertaining to orthopaedic trauma. Despite this, their application and indications for use in trauma remain controversial. This article highlights a number of selected growth factors, other than BMPs, that are currently being investigated in orthopaedic trauma applications. These growth factors have shown significant promise in preclinical and early clinical investigation.
Medical subject headings
- Bone Morphogenetic Proteins
- Fracture Healing
- Fractures, Bone
- Intercellular Signaling Peptides and Proteins
- Wound Healing