Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in women.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 20805275.
- Also identified by DOI 10.2337/dc10-0790 and PMC identifier 2928356.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
To determine the association between 25-hydroxyvitamin D (25-OHD) concentration and risk of incident type 2 diabetes. In a nested case-control study conducted among 608 women with newly diagnosed type 2 diabetes and 559 control subjects in the Nurses' Health Study, we measured the association between baseline plasma 25-OHD concentration and risk of incident diabetes. After adjusting for matching factors and diabetes risk factors, including BMI, higher levels of plasma 25-OHD were associated with a lower risk for type 2 diabetes. The odds ratio for incident type 2 diabetes in the top (median 25-OHD, 33.4 ng/ml) versus the bottom (median 25-OHD, 14.4 ng/ml) quartile was 0.52 (95% CI 0.33-0.83). The associations were consistent across subgroups of baseline BMI, age, and calcium intake. Plasma 25-OHD concentration was associated with lower risk of incident type 2 diabetes in women.
Medical subject headings
- Diabetes Mellitus, Type 2
- Vitamin D