Mass spectrometry in high-throughput proteomics: ready for the big time.

Nilsson, Tommy; Mann, Matthias; Aebersold, Ruedi; Yates, John R; Bairoch, Amos; Bergeron, John J M · Nat Methods · 2010

review · Level V

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Abstract

Mass spectrometry has evolved and matured to a level where it is able to assess the complexity of the human proteome. We discuss some of the expected challenges ahead and promising strategies for success.

Medical subject headings