Interpretation of interactions: guide for the perplexed.

Kendler, Kenneth S; Gardner, Charles O · Br J Psychiatry · 2010

editorial · Level V

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Abstract

In this issue, Zammit et al explore how five dichotomised risk factors work together to predict risk for non-affective psychosis in a large Swedish cohort. In this editorial, we review these findings, and comment on both the nature of additive v. multiplicative models and the meaning of statistical interactions.

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