Molecular genetics, imaging and treatment of oligodendroglial tumours.

Jenkinson, Michael D; Walker, Carol; Brodbelt, Andrew R; Wilkins, Simone; Husband, David; Haylock, Brian · Acta Neurochir (Wien) · 2010

review · Level V

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Abstract

The discovery of a genetic signature of chemosensitivity and prognosis in oligodendroglial tumours prompted a new optimism in glioma management. After more than a decade since the initial reports, where do we stand in the current management of oligodendroglial tumours? This review focuses on the latest molecular genetics, imaging characteristics, and recent trials of treatment paradigms for these tumours.

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