The language of histone crosstalk.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20813257.
- Also identified by DOI 10.1016/j.cell.2010.08.011 and PMC identifier 3711869.
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Abstract
It has been suggested that a specific pattern of histone posttranslational modifications and their crosstalk may constitute a code that determines transcriptional outcomes. However, recent studies indicate that histone modifications have context-dependent effects, making their interplay more like a language within the chromatin signaling pathway than a code.
Medical subject headings
- Chromatin
- Histones
- Protein Processing, Post-Translational