Squamous cell carcinoma arising from a localized vulval lesion of Hailey-Hailey disease after tacrolimus therapy.

von Felbert, Verena; Hampl, Monika; Talhari, Carolina; Engers, Rainer; Megahed, Mosaad · Am J Obstet Gynecol · 2010

case_report · Level V

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Abstract

Hailey-Hailey disease (HHD) is a rare, autosomal dominant intraepidermal blistering disorder characterized by recurrent vesicles and erosions affecting mostly the intertriginous areas. We report a case of HHD affecting exclusively the vulva from which an invasive squamous cell carcinoma developed after tacrolimus therapy.

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