Cervical funneling: effect on gestational length and ultrasound-indicated cerclage in high-risk women.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 20816149.
- Also identified by DOI 10.1016/j.ajog.2010.07.002 and PMC identifier 2935912.
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Abstract
The purpose of this study was to assess funnel type and pregnancy duration in women with previous spontaneous preterm birth and cervical length <25 mm. We performed a secondary analysis of a multicenter randomized trial of cerclage. At the randomization scan that documented short cervix, the presence and type of funnel (U or V) were recorded. One hundred forty-seven of 301 women (49%) had funneling: V-shaped funnel, 99 women; U-shaped funnel, 48 women. U-shaped funnel was associated significantly with preterm birth at <24, <28, <35, and <37 weeks of gestation. In multivariable models that controlled for randomization cervical length and cerclage, women with U-shaped funnel delivered earlier than women with either V-shaped funnel or no funnel. Interaction between cerclage and U-shaped funnel was observed, and analyses that were stratified by cerclage showed that women with a U-shaped funnel and cerclage delivered at a mean of 33.8 +/- 6.6 weeks of gestation, compared with women who did not receive cerclage (28.9 +/- 6.9 weeks of gestation). U-shaped funnels in high-risk women with a short cervix are associated with earlier birth.
Medical subject headings
- Amnion
- Cerclage, Cervical
- Cervix Uteri
- Gestational Age
- Premature Birth