Fluidic microstructuring of alginate hydrogels for the single cell niche.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20820482.
- Also identified by DOI 10.1039/c004988c.
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Abstract
Controlling alginate gel formation by diffusion of Ca(2+) ions through a filter barrier, a layer-by-layer deposition technique with resolution on the size scale of a single cell is presented. It offers the possibility of exposing cells under biocompatible conditions to microheterogeneous three-dimensional environments, mimicking the layered structure of extracellular matrix in tissues.
Medical subject headings
- Alginates
- Flow Cytometry
- Microfluidic Analytical Techniques
- Micromanipulation