An in silico design for a DNA nanomechanical switch.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20828145.
- Also identified by DOI 10.1021/nn1014038.
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Abstract
We have calculated how the charge transfer properties of DNA change in response to the application of an external stretching force. Since charge transfer occurs through the DNA π-stack, any disruption to this stacking causes dramatic changes in the transport properties of the biomolecule, as our calculations demonstrate. We therefore propose that the mechanical response of DNA to an applied stretching force might be used in the design of a nanomechanical switch.
Medical subject headings
- DNA
- Nanoparticles
- Nanotechnology