Zinc transmetallation and gadolinium retention after MR imaging: case report.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20829541.
- Also identified by DOI 10.1148/radiol.10100560.
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Abstract
A patient with chronic zinc poisoning from denture cream retained gadolinium after a magnetic resonance imaging procedure, likely due to transmetallation. During chelation therapy, high levels of gadolinium in excreted urine (up to 89 μg/d, 29 days after gadolinium administration) were present, indicating that gadolinium had been retained. Almost 2½ years after gadolinium exposure, a 24-hour urine collection indicated that the gadolinium level remained in the elevated range (0.6 μg/d). This single case report suggests that patients with elevated zinc exposure may be at increased risk of gadolinium retention.
Medical subject headings
- Carboxymethylcellulose Sodium
- Gadolinium DTPA
- Magnetic Resonance Imaging
- Polymers
- Zinc