Influenza exits the cell without an ESCRT.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20850005.
- Also identified by DOI 10.1016/j.cell.2010.08.036.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Many enveloped viruses depend on the membrane remodeling machinery of their host cells to complete their life cycle. In this issue, Rossman et al. (2010) now demonstrate that influenza virus possesses its own device for releasing nascent virus particles from the plasma membrane, the M2 proton-selective ion channel, which can substitute for the host cell's ESCRT pathway.