Location, location, location-makes all the difference for hypoxia in lung tumors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20858842.
- Also identified by DOI 10.1158/1078-0432.CCR-10-2004 and PMC identifier 3625627.
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Abstract
Hypoxia is a clinically important component of the tumor microenvironment because it adversely affects progression, metastasis, response to chemoradiation therapy, and overall patient survival. Here, we describe how different animal tumor models of lung cancer can yield surprisingly different hypoxic profiles.
Medical subject headings
- Lung Neoplasms
- Tumor Microenvironment