Comment on "The origins of sexually transmitted HIV among men who have sex with men".

Heath, Laura; Frenkel, Lisa M; Foley, Brian T; Mullins, James I · Sci Transl Med · 2010

editorial · Level V

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Abstract

Whether HIV from seminal cells or free HIV in semen is the origin of transmitted virus has important implications for the design of transmission prevention strategies. We found that a recent claim that HIV originates from seminal plasma and not from seminal cells was erroneous, because it was based on biological specimens that had been mislabeled, mixed-up, or contaminated. The origin of transmitted virus from semen therefore remains an open question.

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