In obesity and weight loss, all roads lead to the mighty macrophage.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20877005.
- Also identified by DOI 10.1172/JCI44721 and PMC identifier 2947244.
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Abstract
Obesity is associated with infiltration of white adipose tissue (WAT) by macrophages, which contributes to the development of insulin resistance. In this issue of the JCI, Kosteli and colleagues demonstrate that weight loss is unexpectedly also associated with rapid, albeit transient, recruitment of macrophages to WAT and that this appears to be related to lipolysis.
Medical subject headings
- Adipose Tissue, White
- Lipolysis
- Macrophages
- Obesity
- Weight Loss