What infants and breasts can teach us about natural protection from HIV infection.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20887226.
- Also identified by DOI 10.1086/655972 and PMC identifier 2951298.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Most individuals exposed to human immunodeficiency virus (HIV), adults and children alike, do not become infected. Understanding the basis of this protection depends on systematically and comprehensively defining factors that determine the infectiousness of the host and the susceptibility of the recipient. Successful transmission depends on the relative balance between infectiousness and susceptibility, both of which are influenced by biologic, behavioral, and environmental factors. In this review, we discuss the advantages and disadvantages of mother‐to‐child HIV transmission as a model in which to elucidate correlates of immune protection.
Medical subject headings
- Breast Feeding
- HIV Infections
- Infectious Disease Transmission, Vertical