Expansion of human cord blood hematopoietic stem cells for transplantation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20887947.
- Also identified by DOI 10.1016/j.stem.2010.09.001 and PMC identifier 2962561.
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Abstract
A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture (Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.
Medical subject headings
- Fetal Blood
- Hematopoietic Stem Cell Transplantation
- Hematopoietic Stem Cells