Bilirubin, copper-porphyrins, and the bronze-baby syndrome.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20888578.
- Also identified by DOI 10.1016/j.jpeds.2010.08.014.
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Abstract
Controlled in vitro spectroscopic measurements reveal that bilirubin does not photosensitize the degradation of copper-porphyrins, as has been proposed for the mechanism of the bronze-baby syndrome, an uncommon side-effect of phototherapy. Calculations also show that copper-porphyrins are unlikely to cause the "bronzing." In conclusion, the copper-porphyrin hypothesis is photochemically implausible.
Medical subject headings
- Bilirubin
- Copper
- Porphyrins