Chembench: a cheminformatics workbench.

Walker, Theo; Grulke, Christopher M; Pozefsky, Diane; Tropsha, Alexander · Bioinformatics · 2010

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Abstract

Advances in the field of cheminformatics have been hindered by a lack of freely available tools. We have created Chembench, a publicly available cheminformatics portal for analyzing experimental chemical structure-activity data. Chembench provides a broad range of tools for data visualization and embeds a rigorous workflow for creating and validating predictive Quantitative Structure-Activity Relationship models and using them for virtual screening of chemical libraries to prioritize the compound selection for drug discovery and/or chemical safety assessment. Freely accessible at: http://chembench.mml.unc.edu alex_tropsha@unc.edu

Medical subject headings