Oncogenic osteomalacia: Problems in diagnosis and long-term management.

Dhammi, Ish K; Jain, Anil K; Singh, Ajay Pal; Mishra, Puneet; Jain, Saurabh · Indian J Orthop · 2010

case_series · Level IV

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Abstract

Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the lesion responsible for producing the osteomalacia is excised. For a clinical diagnosis a high index of suspicion is necessary. We present three such cases where in one the oncogenic osteomalacia reversed while in rest it did not. We present this case report to sensitize about the entity.