Label-free biosensing based on single gold nanostars as plasmonic transducers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20942444.
- Also identified by DOI 10.1021/nn100760f.
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Abstract
Gold nanostars provide high sensitivity for single nanoparticle label-free biosensing. The nanostars present multiple plasmon resonances of which the lower energy ones, corresponding to the nanostar tips and core-tip interactions, are the most sensitive to environmental changes. Streptavidin molecules are detected upon binding to individual, biotin-modified gold nanostars by spectral shifts in the plasmon resonances. Concentrations as low as 0.1 nM produce a shift of the tip related plasmon resonances of about 2.3 nm (5.3 meV).
Medical subject headings
- Gold
- Metal Nanoparticles
- Nanostructures
- Surface Plasmon Resonance
- Transducers