Overcoming obstacles to developing new analgesics.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20948534.
- Also identified by DOI 10.1038/nm.2230.
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Abstract
Despite substantial investment by the pharmaceutical industry over several decades, there has been little progress in developing new, efficacious and safe analgesics. As a result, many large pharmaceutical companies are leaving the area of pain medication. Nevertheless, the chances of success could increase if analgesic drug development strategy changed. To achieve such a paradigm shift we must understand why development of drugs for pain relief is so challenging.
Medical subject headings
- Analgesics
- Drug Discovery