High-throughput injection with microfluidics using picoinjectors.

Abate, Adam R; Hung, Tony; Mary, Pascaline; Agresti, Jeremy J; Weitz, David A · Proc Natl Acad Sci U S A · 2010

basic_science · Level V

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Abstract

Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of reagent using electro-microfluidics at kilohertz rates. It can also perform multiple injections for serial and combinatorial additions.

Medical subject headings