Interfacial tension controlled fusion of individual femtolitre droplets and triggering of confined chemical reactions on demand.

Jung, Seung-Yong; Retterer, Scott T; Collier, C Patrick · Lab Chip · 2010

basic_science · Level V

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Abstract

This paper describes stepwise on-demand generation and fusion of femtolitre aqueous droplets based on interfacial tension. Sub-millisecond reaction times from droplet fusion were demonstrated, as well as a reversible chemical toggle switch based on alternating fusion of droplets containing acidic or basic solution, monitored with the pH-dependent emission of fluorescein.

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