Monocytes join the dendritic cell family.
basic_science · Level V
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- Record sourced from PubMed, PMID 21029856.
- Also identified by DOI 10.1016/j.cell.2010.10.022.
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Abstract
Dendritic cells are professional antigen-presenting cells that mediate immunity and tolerance. Cheong et al. (2010) uncover a new route for dendritic cell production in vivo. They show that in response to infection by gram-negative bacteria, monocytes are recruited to the lymph node where they rapidly differentiate into dendritic cells that present antigens to T cells.