Pandemic influenza A (H1N1) outbreak among 15 school-aged HIV-1-infected children.

Feiterna-Sperling, Cornelia; Edelmann, Anke; Nickel, Renate; Magdorf, Klaus; Bergmann, Frank; Rautenberg, Peter; Schweiger, Brunhilde; Wahn, Volker et al. · Clin Infect Dis · 2010

case_series · Level IV

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Abstract

Patients infected with human immunodeficiency virus type 1 (HIV-1) are considered to be at increased risk for 2009 H1N1 influenza-related complications. We performed an observational study after an outbreak of 2009 H1N1 influenza virus infection among a group of 15 HIV-1-infected school-aged children in Germany in October 2009. Clinical course, kinetics of viral shedding, and antibody response among children with CD4 cell counts >350 cells/μL and 2009 H1N1 influenza virus coinfection did not appear to differ from that among healthy children. Oseltamivir shortened the duration of viral shedding.

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