Extinction of Xist improves cloning.
basic_science · Level V
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- Record sourced from PubMed, PMID 21040894.
- Also identified by DOI 10.1016/j.stem.2010.10.003.
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Abstract
Mammalian cloning by somatic cell nuclear transfer is a notoriously inefficient process with a low birth rate. Recently in Science, Inoue et al. (2010) report that somatic cell nuclear transfer fails to regulate Xist expression from the X chromosome.