Hyperbranched polyglycerols on the nanometer and micrometer scale.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 21047679.
- Also identified by DOI 10.1016/j.biomaterials.2010.10.010.
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Abstract
We report the preparation of polyglycerol particles on different length scales by extending the size of hyperbranched polyglycerols (3 nm) to nanogels (32 nm) and microgels (140 and 220 μm). We use miniemulsion templating for the preparation of nanogels and microfluidic templating for the preparation of microgels, which we obtain through a free-radical polymerization of hyperbranched polyglycerol decaacrylate and polyethylene glycol-diacrylate. The use of mild polymerization conditions allows yeast cells to be encapsulated into the resultant microgels with cell viabilities of approximately 30%.
Medical subject headings
- Biocompatible Materials
- Glycerol
- Polyethylene Glycols
- Polyethyleneimine
- Polymers